View source for 1rg2

{{Seed}}
[[Image:1rg2.png|left|200px]]

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{{STRUCTURE_1rg2|  PDB=1rg2  |  SCENE=  }} 

===Crystal structure of human Tyrosyl-DNA Phosphodiesterase complexed with vanadate, octopamine, and tetranucleotide AGTA===


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{{ABSTRACT_PUBMED_14761185}}

==Disease==
Known disease associated with this structure: Spinocerebellar ataxia, autosomal recessive with axonal neuropathy OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607198 607198]]

==About this Structure==
1RG2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RG2 OCA]. 

==Reference==
Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes., Davies DR, Interthal H, Champoux JJ, Hol WG, J Med Chem. 2004 Feb 12;47(4):829-37. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14761185 14761185]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Champoux, J J.]]
[[Category: Davies, D R.]]
[[Category: Hol, W G.]]
[[Category: Interthal, H.]]
[[Category: Protein-dna complex]]
[[Category: Transition state mimic]]
[[Category: Vanadate complex]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 15:20:47 2008''