View source for 2uzu

{{Seed}}
[[Image:2uzu.png|left|200px]]

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{{STRUCTURE_2uzu|  PDB=2uzu  |  SCENE=  }} 

===PKA STRUCTURES OF INDAZOLE-PYRIDINE SERIES OF AKT INHIBITORS===


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{{ABSTRACT_PUBMED_17523610}}

==About this Structure==
2UZU is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UZU OCA]. 

==Reference==
Syntheses of potent, selective, and orally bioavailable indazole-pyridine series of protein kinase b/akt inhibitors with reduced hypotension., Zhu GD, Gandhi VB, Gong J, Thomas S, Woods KW, Song X, Li T, Diebold RB, Luo Y, Liu X, Guan R, Klinghofer V, Johnson EF, Bouska J, Olson A, Marsh KC, Stoll VS, Mamo M, Polakowski J, Campbell TJ, Martin RL, Gintant GA, Penning TD, Li Q, Rosenberg SH, Giranda VL, J Med Chem. 2007 Jun 28;50(13):2990-3003. Epub 2007 May 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17523610 17523610]
[[Category: Bos taurus]]
[[Category: Protein complex]]
[[Category: CAMP-dependent protein kinase]]
[[Category: Bouska, J.]]
[[Category: Campbell, T J.]]
[[Category: Diebold, R B.]]
[[Category: Gandhi, V B.]]
[[Category: Giranda, V L.]]
[[Category: Gong, J.]]
[[Category: Guan, R.]]
[[Category: Johnson, E F.]]
[[Category: Klinghofer, V.]]
[[Category: Li, Q.]]
[[Category: Li, T.]]
[[Category: Liu, X.]]
[[Category: Luo, Y.]]
[[Category: Mamo, M.]]
[[Category: Marsh, K C.]]
[[Category: Olson, A.]]
[[Category: Penning, T D.]]
[[Category: Polakowski, J.]]
[[Category: Rosenberg, S H.]]
[[Category: Song, X.]]
[[Category: Stoll, V S.]]
[[Category: Thomas, S.]]
[[Category: Woods, K W.]]
[[Category: Zhu, G D.]]
[[Category: Akt inhibitor]]
[[Category: Atp-binding]]
[[Category: Camp]]
[[Category: Kinase]]
[[Category: Lipoprotein]]
[[Category: Myristate]]
[[Category: Nuclear protein]]
[[Category: Nucleotide-binding]]
[[Category: Phosphorylation]]
[[Category: Protein kinase some]]
[[Category: Protein kinase inhibitor]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]

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