View source for 1g49

{{Seed}}
[[Image:1g49.png|left|200px]]

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{{STRUCTURE_1g49|  PDB=1g49  |  SCENE=  }} 

===A CARBOXYLIC ACID BASED INHIBITOR IN COMPLEX WITH MMP3===


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{{ABSTRACT_PUBMED_11150165}}

==Disease==
Known disease associated with this structure: Coronary heart disease, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=185250 185250]]

==About this Structure==
1G49 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G49 OCA]. 

==Reference==
Development of new hydroxamate matrix metalloproteinase inhibitors derived from functionalized 4-aminoprolines., Natchus MG, Bookland RG, De B, Almstead NG, Pikul S, Janusz MJ, Heitmeyer SA, Hookfin EB, Hsieh LC, Dowty ME, Dietsch CR, Patel VS, Garver SM, Gu F, Pokross ME, Mieling GE, Baker TR, Foltz DJ, Peng SX, Bornes DM, Strojnowski MJ, Taiwo YO, J Med Chem. 2000 Dec 28;43(26):4948-63. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11150165 11150165]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Stromelysin 1]]
[[Category: Almstead, N G.]]
[[Category: Bookland, R G.]]
[[Category: De, B.]]
[[Category: Natchus, M G.]]
[[Category: Pikul, S.]]
[[Category: Inhibited]]
[[Category: Mixed alpha beta structure]]
[[Category: Zinc protease]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 04:23:30 2008''