View source for 1af9

[[Image:1af9.jpg|left|200px]]<br /><applet load="1af9" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="1af9, resolution 2.7&Aring;" />
'''TETANUS NEUROTOXIN C FRAGMENT'''<br />

==Overview==
The 2.7 A structure of the tetanus neurotoxin receptor binding fragment Hc, reveals a jelly-roll domain and a beta-trefoil domain. Hc retains the, unique transport properties of the holotoxin and is capable of eliciting a, protective immunological response against the full length holotoxin.

==About this Structure==
1AF9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_tetani Clostridium tetani]. Active as [http://en.wikipedia.org/wiki/Tentoxilysin Tentoxilysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.68 3.4.24.68] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AF9 OCA]. 

==Reference==
Structure of the receptor binding fragment HC of tetanus neurotoxin., Umland TC, Wingert LM, Swaminathan S, Furey WF, Schmidt JJ, Sax M, Nat Struct Biol. 1997 Oct;4(10):788-92. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9334741 9334741]
[[Category: Clostridium tetani]]
[[Category: Single protein]]
[[Category: Tentoxilysin]]
[[Category: Furey, W.F.]]
[[Category: Sax, M.]]
[[Category: Schmidt, J.J.]]
[[Category: Swaminathan, S.]]
[[Category: Umland, T.C.]]
[[Category: Wingert, L.]]
[[Category: clostridial neurotoxin]]
[[Category: receptor binding]]
[[Category: tetanus]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 10:48:36 2007''