View source for 2qdf

[[Image:2qdf.jpg|left|200px]]

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{{STRUCTURE_2qdf|  PDB=2qdf  |  SCENE=  }} 

'''Structure of N-terminal domain of E. Coli YaeT'''


==Overview==
Integral beta-barrel proteins are found in the outer membranes of mitochondria, chloroplasts, and Gram-negative bacteria. The machine that assembles these proteins contains an integral membrane protein, called YaeT in Escherichia coli, which has one or more polypeptide transport-associated (POTRA) domains. The crystal structure of a periplasmic fragment of YaeT reveals the POTRA domain fold and suggests a model for how POTRA domains can bind different peptide sequences, as required for a machine that handles numerous beta-barrel protein precursors. Analysis of POTRA domain deletions shows which are essential and provides a view of the spatial organization of this assembly machine.

==About this Structure==
2QDF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDF OCA]. 

==Reference==
Structure and function of an essential component of the outer membrane protein assembly machine., Kim S, Malinverni JC, Sliz P, Silhavy TJ, Harrison SC, Kahne D, Science. 2007 Aug 17;317(5840):961-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17702946 17702946]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Harrison, S C.]]
[[Category: Kahne, D.]]
[[Category: Kim, S.]]
[[Category: Malinverni, J C.]]
[[Category: Silhavy, T J.]]
[[Category: Sliz, P.]]
[[Category: Membrane protein]]
[[Category: Potra domain]]
[[Category: Protein transport]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 14:46:12 2008''