View source for 2zav

[[Image:2zav.gif|left|200px]]<br />
<applet load="2zav" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="2zav, resolution 1.70&Aring;" />
'''Arginase I (homo sapiens): native and unliganded structure at 1.70 A resolution'''<br />

==About this Structure==
2ZAV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with MN as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Arginase Arginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.3.1 3.5.3.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2ZAV OCA]. 

==Reference==
Crystal structure of human arginase I complexed with thiosemicarbazide reveals an unusual thiocarbonyl mu-sulfide ligand in the binuclear manganese cluster., Di Costanzo L, Pique ME, Christianson DW, J Am Chem Soc. 2007 May 23;129(20):6388-9. Epub 2007 May 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17469833 17469833]
[[Category: Arginase]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Christianson, D.W.]]
[[Category: Costanzo, L.Di.]]
[[Category: MN]]
[[Category: alternative splicing]]
[[Category: apical water]]
[[Category: arginine metabolism]]
[[Category: cytoplasm]]
[[Category: disease mutation]]
[[Category: hydrolase]]
[[Category: manganese cluster coordination]]
[[Category: metal-binding]]
[[Category: phosphorylation]]
[[Category: polymorphism]]
[[Category: proton wire]]
[[Category: urea cycle]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 23:47:31 2007''