View source for 1ymc

[[Image:1ymc.jpg|left|200px]]

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{{STRUCTURE_1ymc|  PDB=1ymc  |  SCENE=  }} 

'''THREE-DIMENSIONAL STRUCTURE OF CYANOMET-SULFMYOGLOBIN C'''


==Overview==
The atomic structure of horse heart cyanomet-sulfmyoglobin C has been established by x-ray crystallographic techniques to a resolution of 2.0 A with an R value of 0.129. The protoheme IX prosthetic group of this thermodynamically stable sulfmyoglobin derivative has been converted to a chlorin in which the pyrrole ring bearing the 4-vinyl group is saturated and possesses an exocyclic thiolene ring. This study provides the three-dimensional structure of a protein with an iron-chlorin prosthetic group. The overall conformation of the surrounding polypeptide chain of the modified protein is very similar to that of the native protein. However, the addition of the sulfur atom has caused a distortion of the prosthetic group from that in the native protein to result in the repositioning of the side chains of some residues in the heme pocket.

==About this Structure==
1YMC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YMC OCA]. 

==Reference==
Three-dimensional structure of cyanomet-sulfmyoglobin C., Evans SV, Sishta BP, Mauk AG, Brayer GD, Proc Natl Acad Sci U S A. 1994 May 24;91(11):4723-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8197124 8197124]
[[Category: Equus caballus]]
[[Category: Single protein]]
[[Category: Brayer, G D.]]
[[Category: Evans, S V.]]
[[Category: Oxygen transport]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 16:30:32 2008''