View source for 3sqp


==Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity==
<StructureSection load='3sqp' size='340' side='right'caption='[[3sqp]], [[Resolution|resolution]] 2.21&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sqp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SQP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3J8:5-METHYLPHENAZIN-1(5H)-ONE'>3J8</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sqp OCA], [https://pdbe.org/3sqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sqp RCSB], [https://www.ebi.ac.uk/pdbsum/3sqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sqp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSHR_HUMAN GSHR_HUMAN] Maintains high levels of reduced glutathione in the cytosol.

==See Also==
*[[Glutathione Reductase|Glutathione Reductase]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Fritz-Wolf K]]
[[Category: Goebel U]]
[[Category: Koenig I]]
[[Category: Schirmer RH]]