View source for 3si1


==Structure of glycosylated murine glutaminyl cyclase==
<StructureSection load='3si1' size='340' side='right'caption='[[3si1]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3si1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SI1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SI1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3si1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3si1 OCA], [https://pdbe.org/3si1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3si1 RCSB], [https://www.ebi.ac.uk/pdbsum/3si1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3si1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/QPCT_MOUSE QPCT_MOUSE] Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue (By similarity).

==See Also==
*[[Glutaminyl cyclase|Glutaminyl cyclase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Carrillo D]]
[[Category: Dambe T]]
[[Category: Parthier C]]
[[Category: Stubbs MT]]