View source for 5sbm


==CD44 PanDDA analysis group deposition -- The hyaluronan-binding domain of CD44 in complex with Z1267885772==
<StructureSection load='5sbm' size='340' side='right'caption='[[5sbm]], [[Resolution|resolution]] 1.14&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5sbm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5SBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5SBM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.14&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8AB:(3S)-3-methyl-1-(6-methylpyridin-2-yl)piperazine'>8AB</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5sbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5sbm OCA], [https://pdbe.org/5sbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5sbm RCSB], [https://www.ebi.ac.uk/pdbsum/5sbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5sbm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Bezerra GA]]
[[Category: Bountra C]]
[[Category: Bradshaw WJ]]
[[Category: Brennan PE]]
[[Category: Gileadi O]]
[[Category: Katis VL]]
[[Category: Koekemoer L]]
[[Category: Von Delft F]]