View source for 2mla


==Solution structure of BmKTX-D19K==
<StructureSection load='2mla' size='340' side='right'caption='[[2mla]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2mla]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_martensii Mesobuthus martensii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MLA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mla OCA], [https://pdbe.org/2mla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mla RCSB], [https://www.ebi.ac.uk/pdbsum/2mla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mla ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KAX36_MESMA KAX36_MESMA] Blocks voltage-gated potassium channels. At 2 uM, blocks rat Kv1.1/KCNA1 and Kv1.3/KCNA3, has a strong effect on rat Kv1.2/KCNA2 and Kv1.6/KCNA6 as well as a moderate effect on Shaker IR.<ref>PMID:9354615</ref> <ref>PMID:20713119</ref> 

==See Also==
*[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mesobuthus martensii]]
[[Category: Chen Z]]
[[Category: Hong J]]
[[Category: Lin D]]
[[Category: Wu Y]]