View source for 3aeb


==Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Phenoxy-phenyl)-2-trifluoromethyl-benzamide==
<StructureSection load='3aeb' size='340' side='right'caption='[[3aeb]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3aeb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AEB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=F7A:N-(3-PHENOXYPHENYL)-2-(TRIFLUOROMETHYL)BENZAMIDE'>F7A</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aeb OCA], [https://pdbe.org/3aeb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aeb RCSB], [https://www.ebi.ac.uk/pdbsum/3aeb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aeb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SDHA_PIG SDHA_PIG] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity).

==See Also==
*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Harada S]]
[[Category: Honma T]]
[[Category: Inaoka DK]]
[[Category: Inoue M]]
[[Category: Kido Y]]
[[Category: Kita K]]
[[Category: Mao J]]
[[Category: Matsuoka S]]
[[Category: Omori J]]
[[Category: Osanai A]]
[[Category: Sakamoto K]]
[[Category: Sasaki T]]
[[Category: Shindo M]]
[[Category: Tanaka A]]