View source for 2dcg


==MOLECULAR STRUCTURE OF A LEFT-HANDED DOUBLE HELICAL DNA FRAGMENT AT ATOMIC RESOLUTION==
<StructureSection load='2dcg' size='340' side='right'caption='[[2dcg]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2dcg]] is a 2 chain structure. The November 2001 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''DNA''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2001_11 10.2210/rcsb_pdb/mom_2001_11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DCG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DCG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dcg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dcg OCA], [https://pdbe.org/2dcg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dcg RCSB], [https://www.ebi.ac.uk/pdbsum/2dcg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dcg ProSAT]</span></td></tr>
</table>
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== Publication Abstract from PubMed ==
The DNA fragment d(CpGpCpGpCpG) crystallises as a left-handed double helical molecule with Watson-Crick base pairs and an antiparallel organisation of the sugar phosphate chains. The helix has two nucleotides in the asymmetric unit and contains twelve base pairs per turn. It differs significantly from right-handed B-DNA.

Molecular structure of a left-handed double helical DNA fragment at atomic resolution.,Wang AH, Quigley GJ, Kolpak FJ, Crawford JL, van Boom JH, van der Marel G, Rich A Nature. 1979 Dec 13;282(5740):680-6. PMID:514347<ref>PMID:514347</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 2dcg" style="background-color:#fffaf0;"></div>
== References ==
<references/>
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</StructureSection>
[[Category: DNA]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Crawford JL]]
[[Category: Kolpak FJ]]
[[Category: Quigley GJ]]
[[Category: Rich A]]
[[Category: Van Boom JH]]
[[Category: Van Der Marel GA]]
[[Category: Wang AH-J]]