View source for 8akm


==Acyl-enzyme complex of ertapenem bound to deacylation mutant KPC-2 (E166Q)==
<StructureSection load='8akm' size='340' side='right'caption='[[8akm]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8akm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AKM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=N9X:Ertapenem'>N9X</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8akm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8akm OCA], [https://pdbe.org/8akm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8akm RCSB], [https://www.ebi.ac.uk/pdbsum/8akm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8akm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency.
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</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Hinchliffe P]]
[[Category: Spencer J]]
[[Category: Tooke CL]]