View source for 7zhy


==Leishmania donovani Glucose 6-Phosphate Dehydrogenase C138S mutant complexed with NADP(H)==
<StructureSection load='7zhy' size='340' side='right'caption='[[7zhy]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7zhy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_donovani Leishmania donovani]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZHY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZHY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zhy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zhy OCA], [https://pdbe.org/7zhy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zhy RCSB], [https://www.ebi.ac.uk/pdbsum/7zhy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zhy ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A2CIL3_LEIDO A2CIL3_LEIDO] Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.[RuleBase:RU362120]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Leishmania donovani]]
[[Category: Berneburg I]]
[[Category: Fritz-Wolf K]]