View source for 4hcc


==The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex==
<StructureSection load='4hcc' size='340' side='right'caption='[[4hcc]], [[Resolution|resolution]] 2.96&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hcc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_DH5alpha Escherichia coli DH5alpha]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HCC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hcc OCA], [https://pdbe.org/4hcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hcc RCSB], [https://www.ebi.ac.uk/pdbsum/4hcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hcc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EX1_ECOLI EX1_ECOLI] Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase.

==See Also==
*[[Exonuclease 3D structures|Exonuclease 3D structures]]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Gong W]]
[[Category: Ji C]]
[[Category: Liu M]]
[[Category: Lou T]]
[[Category: Qiu R]]
[[Category: Wei J]]