View source for 4jrm


==Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio Cholerae (space group P212121) at 1.75 Angstrom==
<StructureSection load='4jrm' size='340' side='right'caption='[[4jrm]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4jrm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibch Vibch]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JRM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JRM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabF, VC2019, VC_2019 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243277 VIBCH])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_II Beta-ketoacyl-[acyl-carrier-protein] synthase II], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.179 2.3.1.179] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jrm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jrm OCA], [https://pdbe.org/4jrm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jrm RCSB], [https://www.ebi.ac.uk/pdbsum/4jrm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jrm ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/FABF_VIBCH FABF_VIBCH]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis (By similarity). 

==See Also==
*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Vibch]]
[[Category: Anderson, W F]]
[[Category: Structural genomic]]
[[Category: Chruszcz, M]]
[[Category: Cooper, D R]]
[[Category: Hou, J]]
[[Category: Minor, W]]
[[Category: Shabalin, I G]]
[[Category: Zheng, H]]
[[Category: Csgid]]
[[Category: Fabf]]
[[Category: Transferase]]
[[Category: Vibrio cholerae]]