View source for 3ist


==Crystal structure of glutamate racemase from Listeria monocytogenes in complex with succinic acid==
<StructureSection load='3ist' size='340' side='right'caption='[[3ist]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ist]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lismo Lismo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IST FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3hfr|3hfr]], [[3isv|3isv]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lmo1237, murI, racE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=169963 LISMO])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutamate_racemase Glutamate racemase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.3 5.1.1.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ist FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ist OCA], [https://pdbe.org/3ist PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ist RCSB], [https://www.ebi.ac.uk/pdbsum/3ist PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ist ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/MURI_LISMO MURI_LISMO]] Provides the (R)-glutamate required for cell wall biosynthesis (By similarity). 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/is/3ist_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ist ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Glutamate racemase 3D structures|Glutamate racemase 3D structures]]
__TOC__
</StructureSection>
[[Category: Glutamate racemase]]
[[Category: Large Structures]]
[[Category: Lismo]]
[[Category: Anderson, W F]]
[[Category: Bujnicki, J M]]
[[Category: Structural genomic]]
[[Category: Chruszcz, M]]
[[Category: Majorek, K A]]
[[Category: Minor, W]]
[[Category: Onopriyenko, O]]
[[Category: Savchenko, A]]
[[Category: Skarina, T]]
[[Category: Stam, J]]
[[Category: Cell shape]]
[[Category: Cell wall biogenesis/degradation]]
[[Category: Csgid]]
[[Category: Isomerase]]
[[Category: Peptidoglycan synthesis]]