View source for 2dyc


==Crystal structure of the N-terminal domain of mouse galectin-4==
<StructureSection load='2dyc' size='340' side='right'caption='[[2dyc]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2dyc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DYC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DYC FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dyc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dyc OCA], [https://pdbe.org/2dyc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dyc RCSB], [https://www.ebi.ac.uk/pdbsum/2dyc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dyc ProSAT], [https://www.topsan.org/Proteins/RSGI/2dyc TOPSAN]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/LEG4_MOUSE LEG4_MOUSE]] Galectin that binds lactose and a related range of sugars (By similarity). 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dy/2dyc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dyc ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Galectin 3D structures|Galectin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Kato-Murayama, M]]
[[Category: Murayama, K]]
[[Category: Structural genomic]]
[[Category: Shirouzu, M]]
[[Category: Terada, T]]
[[Category: Yokoyama, S]]
[[Category: Gal-bind lectin]]
[[Category: Galectin]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Sugar binding]]
[[Category: Sugar binding protein]]