View source for 2qt2


==Cyclized-Dehydrated Intermediate of GFP Variant Q183E in Chromophore Maturation==
<StructureSection load='2qt2' size='340' side='right'caption='[[2qt2]], [[Resolution|resolution]] 1.31&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2qt2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeqvi Aeqvi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QT2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QT2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CJO:[(2R,4R)-2-[(1R,2R)-1-AMINO-2-HYDROXYPROPYL]-4-(4-HYDROXYBENZYL)-5-OXOIMIDAZOLIDIN-1-YL]ACETIC+ACID'>CJO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2qrf|2qrf]], [[2qz0|2qz0]], [[2awj|2awj]], [[2awl|2awl]], [[2awm|2awm]], [[1ema|1ema]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GFP ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6100 AEQVI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qt2 OCA], [https://pdbe.org/2qt2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qt2 RCSB], [https://www.ebi.ac.uk/pdbsum/2qt2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qt2 ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/GFP_AEQVI GFP_AEQVI]] Energy-transfer acceptor. Its role is to transduce the blue chemiluminescence of the protein aequorin into green fluorescent light by energy transfer. Fluoresces in vivo upon receiving energy from the Ca(2+)-activated photoprotein aequorin. 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qt/2qt2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qt2 ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Green Fluorescent Protein 3D structures|Green Fluorescent Protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Aeqvi]]
[[Category: Large Structures]]
[[Category: Barondeau, D P]]
[[Category: Getzoff, E D]]
[[Category: Hitomi, C]]
[[Category: Tainer, J A]]
[[Category: Wood, T I]]
[[Category: Chromophore]]
[[Category: Chromophore maturation]]
[[Category: Cyclized]]
[[Category: Dehydrated intermediate]]
[[Category: Fluorescent protein]]
[[Category: Gfp]]
[[Category: Luminescence]]
[[Category: Photoprotein]]