View source for 2b7n


==Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori==
<StructureSection load='2b7n' size='340' side='right'caption='[[2b7n]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2b7n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B7N FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NTM:QUINOLINIC+ACID'>NTM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Nicotinate-nucleotide_diphosphorylase_(carboxylating) Nicotinate-nucleotide diphosphorylase (carboxylating)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.19 2.4.2.19] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b7n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b7n OCA], [https://pdbe.org/2b7n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b7n RCSB], [https://www.ebi.ac.uk/pdbsum/2b7n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b7n ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/NADC_HELPY NADC_HELPY]] Involved in the catabolism of quinolinic acid (QA) (By similarity). 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b7/2b7n_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b7n ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
__TOC__
</StructureSection>
[[Category: Atcc 43504]]
[[Category: Large Structures]]
[[Category: Eom, S H]]
[[Category: Im, Y J]]
[[Category: Kim, M K]]
[[Category: Lee, J H]]
[[Category: Helicobacter pylori]]
[[Category: Quinolinate phosphoribosyltransferase]]
[[Category: Quinolinic acid]]
[[Category: Transferase]]