View source for 1xg7


==Conserved hypothetical protein Pfu-877259-001 from Pyrococcus furiosus==
<StructureSection load='1xg7' size='340' side='right'caption='[[1xg7]], [[Resolution|resolution]] 1.88&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1xg7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XG7 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xg7 OCA], [https://pdbe.org/1xg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1xg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xg7 ProSAT], [https://www.topsan.org/Proteins/SECSG/1xg7 TOPSAN]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/AGOG_PYRFU AGOG_PYRFU]] DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates (By similarity). 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xg/1xg7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xg7 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrfu]]
[[Category: Adams, M W.W]]
[[Category: Chang, J]]
[[Category: Chang, S H]]
[[Category: Chen, C Y]]
[[Category: Chen, L]]
[[Category: Eneh, J C]]
[[Category: Habel, J]]
[[Category: Hopkins, R C]]
[[Category: Horanyi, P]]
[[Category: II, F L.Poole]]
[[Category: III, W B.Arendall]]
[[Category: Jenney, F E]]
[[Category: Lee, D]]
[[Category: Lee, H S]]
[[Category: Li, T]]
[[Category: Lin, D]]
[[Category: Liu, Z J]]
[[Category: Richardson, D C]]
[[Category: Richardson, J S]]
[[Category: Rose, J P]]
[[Category: Structural genomic]]
[[Category: Shah, C]]
[[Category: Sugar, F J]]
[[Category: Tempel, W]]
[[Category: Wang, B C]]
[[Category: Xu, H]]
[[Category: Yang, H]]
[[Category: Zhao, M]]
[[Category: Zhou, W]]
[[Category: Conserved hypothetical protein]]
[[Category: Hyperthermophile]]
[[Category: PSI, Protein structure initiative]]
[[Category: Pyrococcus furiosus]]
[[Category: Secsg]]
[[Category: Unknown function]]