View source for 2ee1


==Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4==
<StructureSection load='2ee1' size='340' side='right'caption='[[2ee1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ee1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EE1 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHD4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ee1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ee1 OCA], [https://pdbe.org/2ee1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ee1 RCSB], [https://www.ebi.ac.uk/pdbsum/2ee1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ee1 ProSAT], [https://www.topsan.org/Proteins/RSGI/2ee1 TOPSAN]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/CHD4_HUMAN CHD4_HUMAN]] Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones.<ref>PMID:9804427</ref> <ref>PMID:17626165</ref>  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/2ee1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ee1 ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Chromodomain-helicase-DNA-binding protein 3D structures|Chromodomain-helicase-DNA-binding protein 3D structures]]
*[[Helicase 3D structures|Helicase 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Harada, T]]
[[Category: Kigawa, T]]
[[Category: Koshiba, S]]
[[Category: Structural genomic]]
[[Category: Sato, M]]
[[Category: Tochio, N]]
[[Category: Watanabe, S]]
[[Category: Yokoyama, S]]
[[Category: Atp- dependent helicase chd4]]
[[Category: Chd-4]]
[[Category: Ec 3 6.1.-]]
[[Category: Mi-2 autoantigen 218 kda protein]]
[[Category: Mi2-beta]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Signaling protein]]