View source for 1wsa

[[Image:1wsa.gif|left|200px]]<br />
<applet load="1wsa" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="1wsa, resolution 2.2&Aring;" />
'''STRUCTURE OF L-ASPARAGINASE II PRECURSOR'''<br />

==Overview==
The amino acid sequence and tertiary structure of Wolinella succinogenes, L-asparaginase were determined, and were compared with the structures of, other type-II bacterial L-asparaginases. Each chain of this homotetrameric, enzyme consists of 330 residues. The amino acid sequence is 40-50%, identical to the sequences of related proteins from other bacterial, sources, and all residues previously shown to be crucial for the catalytic, action of these enzymes are identical. Differences between the amino acid, sequence of W. succinogenes L-asparaginase and that of related enzymes are, discussed in terms of the possible influence on the substrate specificity., The overall fold of the protein subunit is almost identical to that, observed for other L-asparaginases. Two fragments in each subunit, ... [[http://ispc.weizmann.ac.il/pmbin/getpm?8898907 (full description)]]

==About this Structure==
1WSA is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Wolinella_succinogenes Wolinella succinogenes]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.1 3.5.1.1]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1WSA OCA]]. 

==Reference==
Crystal structure and amino acid sequence of Wolinella succinogenes L-asparaginase., Lubkowski J, Palm GJ, Gilliland GL, Derst C, Rohm KH, Wlodawer A, Eur J Biochem. 1996 Oct 1;241(1):201-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8898907 8898907]
[[Category: Single protein]]
[[Category: Wolinella succinogenes]]
[[Category: Derst, C.]]
[[Category: Gilliland, G.L.]]
[[Category: Lubkowski, J.]]
[[Category: Palm, G.J.]]
[[Category: Rohm, K.H.]]
[[Category: Wlodawer, A.]]
[[Category: hydrolase]]
[[Category: periplasmic]]
[[Category: signal]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:56:25 2007''