View source for 3c5c


==Crystal structure of human Ras-like, family 12 protein in complex with GDP==
<StructureSection load='3c5c' size='340' side='right'caption='[[3c5c]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3c5c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C5C OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3C5C FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RASL12, RIS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3c5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c5c OCA], [http://pdbe.org/3c5c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3c5c RCSB], [http://www.ebi.ac.uk/pdbsum/3c5c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3c5c ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/3c5c_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c5c ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Bochkarev, A]]
[[Category: Bountra, C]]
[[Category: Edwards, A M]]
[[Category: Loppnau, P]]
[[Category: Park, H]]
[[Category: Structural genomic]]
[[Category: Shen, L]]
[[Category: Tempel, W]]
[[Category: Tong, Y]]
[[Category: Weigelt, J]]
[[Category: Gdp]]
[[Category: Gtp-binding]]
[[Category: Gtpase]]
[[Category: Limited proteolysis]]
[[Category: Nucleotide-binding]]
[[Category: Ra]]
[[Category: Rasl12]]
[[Category: Sgc]]
[[Category: Signaling protein]]