View source for 5mbl


==Cathepsin B in complex with DARPin 81==
<StructureSection load='5mbl' size='340' side='right'caption='[[5mbl]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5mbl]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MBL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5MBL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SCH:S-METHYL-THIO-CYSTEINE'>SCH</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5mbl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mbl OCA], [http://pdbe.org/5mbl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mbl RCSB], [http://www.ebi.ac.uk/pdbsum/5mbl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mbl ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. 

==See Also==
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
__TOC__
</StructureSection>
[[Category: Cathepsin B]]
[[Category: Large Structures]]
[[Category: Kramer, L]]
[[Category: Renko, M]]
[[Category: Turk, B]]
[[Category: Turk, D]]
[[Category: Complex]]
[[Category: Darpin]]
[[Category: Hydrolase]]
[[Category: Protease]]