View source for 6psf


==Rhinovirus C15 complexed with domains I and II of receptor CDHR3==
<StructureSection load='6psf' size='340' side='right'caption='[[6psf]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6psf]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Rhinovirus_c Rhinovirus c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PSF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PSF FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6psf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6psf OCA], [http://pdbe.org/6psf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6psf RCSB], [http://www.ebi.ac.uk/pdbsum/6psf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6psf ProSAT]</span></td></tr>
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/CDHR3_HUMAN CDHR3_HUMAN]] Asthma susceptibility may be associated with variations affecting the gene represented in this entry in early childhood asthma with severe exacerbations occurring between 2 and 6 years of age.<ref>PMID:24241537</ref>  
== Function ==
[[http://www.uniprot.org/uniprot/CDHR3_HUMAN CDHR3_HUMAN]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  (Microbial infection) Acts as a receptor for rhinovirus C.<ref>PMID:25848009</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rhinovirus c]]
[[Category: Klose, T]]
[[Category: Palmenberg, A C]]
[[Category: Sun, Y]]
[[Category: Watters, K]]
[[Category: Cadherin]]
[[Category: Receptor]]
[[Category: Virus-cell adhesion complex]]