View source for 1hbi

[[Image:1hbi.gif|left|200px]]<br />
<applet load="1hbi" size="450" color="white" frame="true" align="right" spinBox="true" 
caption="1hbi, resolution 1.7&Aring;" />
'''CRYSTAL STRUCTURE OF OXYGENATED SCAPHARCA DIMERIC HEMOGLOBIN AT 1.7 ANGSTROMS RESOLUTION'''<br />

==Overview==
The crystal structure of the cooperative dimeric hemoglobin from the blood, clam Scapharca inaequivalvis has been determined in the oxygenated state, and refined to an R-factor of 0.157 at 1.7-A resolution. The structure is, very similar to the carbon monoxide-liganded form with subtle differences, in ligand binding geometry. Oxygen binds to the heme iron in a bent, conformation with Fe-O-O angles of 135 degrees and 150 degrees for the two, subunits. These observed angles are lower than the equivalent angles in, the carbon monoxide-liganded form and intermediate between the angles, observed in structures of oxygenated sperm whale myoglobin and oxygenated, human hemoglobin. This third high resolution structure of Scapharca, dimeric hemoglobin permits a detailed analysis of the water structure in, the highly hydrated interface between subunits.

==About this Structure==
1HBI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Scapharca_inaequivalvis Scapharca inaequivalvis] with HEM and OXY as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HBI OCA]. 

==Reference==
Crystal structure of oxygenated Scapharca dimeric hemoglobin at 1.7-A resolution., Condon PJ, Royer WE Jr, J Biol Chem. 1994 Oct 14;269(41):25259-67. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7929217 7929217]
[[Category: Scapharca inaequivalvis]]
[[Category: Single protein]]
[[Category: Condon, P.J.]]
[[Category: Junior, W.E.Royer.]]
[[Category: HEM]]
[[Category: OXY]]
[[Category: oxygen transport]]

''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Thu Nov  8 13:04:20 2007''