View source for 2vph


==Crystal structure of the human protein tyrosine phosphatase, non- receptor type 4, PDZ domain==
<StructureSection load='2vph' size='340' side='right'caption='[[2vph]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2vph]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VPH FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cs5|2cs5]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vph OCA], [http://pdbe.org/2vph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vph RCSB], [http://www.ebi.ac.uk/pdbsum/2vph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vph ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vp/2vph_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2vph ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N]]
[[Category: Delft, F von]]
[[Category: Edwards, A]]
[[Category: Elkins, J M]]
[[Category: Filippakopoulos, P]]
[[Category: Kavanagh, K]]
[[Category: Knapp, S]]
[[Category: Pike, A C.W]]
[[Category: Roos, A K]]
[[Category: Wang, J]]
[[Category: Weigelt, J]]
[[Category: Cytoskeleton]]
[[Category: Dephosphorylation]]
[[Category: Hydrolase]]
[[Category: Megakaryocyte]]
[[Category: Protein phosphatase]]
[[Category: Ptpmeg]]
[[Category: Ptpn4]]
[[Category: Structural protein]]