View source for 4owp


==Crystal structure of rpn11 in a heterodimer complex with rpn8, representing the active portion of the proteasome lid.==
<StructureSection load='4owp' size='340' side='right'caption='[[4owp]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4owp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OWP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OWP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4o8x|4o8x]], [[4o8y|4o8y]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">O5360,RPN8,YOR261C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast]), MPR1,RPN11,YFR004W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4owp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4owp OCA], [http://pdbe.org/4owp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4owp RCSB], [http://www.ebi.ac.uk/pdbsum/4owp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4owp ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/RPN8_YEAST RPN8_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9584156</ref>  [[http://www.uniprot.org/uniprot/RPN11_YEAST RPN11_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:21075847</ref>  

==See Also==
*[[Proteasome 3D structures|Proteasome 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Baker's yeast]]
[[Category: Large Structures]]
[[Category: Dvir, H]]
[[Category: Glickman, M H]]
[[Category: Mansour, W]]
[[Category: Nakasone, M A]]
[[Category: Yu, Z]]
[[Category: Deubiquitination]]
[[Category: Hydrolase]]
[[Category: Metalloprotease]]
[[Category: Mpn domain]]
[[Category: Proteasome]]
[[Category: Ubiquitin]]
[[Category: Zinc]]