View source for 6qvj


==HsCKK (human CAMSAP1) decorated 14pf taxol-GDP microtubule==
<StructureSection load='6qvj' size='340' side='right'caption='[[6qvj]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6qvj]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QVJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QVJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6qus|6qus]], [[6quy|6quy]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qvj OCA], [http://pdbe.org/6qvj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qvj RCSB], [http://www.ebi.ac.uk/pdbsum/6qvj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qvj ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/CAMP1_HUMAN CAMP1_HUMAN]] Probable microtubule-binding protein that plays a role in the regulation of cell morphology and cytoskeletal organization. Through interaction with spectrin may regulate neurite outgrowth.<ref>PMID:19508979</ref> <ref>PMID:21834987</ref> <ref>PMID:24117850</ref>  [[http://www.uniprot.org/uniprot/TBB5_HUMAN TBB5_HUMAN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBA1B_HUMAN TBA1B_HUMAN]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Akhmanova, A]]
[[Category: Atherton, J M]]
[[Category: Baldus, M]]
[[Category: Cook, A]]
[[Category: Jiang, K]]
[[Category: Luo, Y]]
[[Category: Moores, C A]]
[[Category: Roll-Mecak, A]]
[[Category: Stangier, M]]
[[Category: Steinmetz, M O]]
[[Category: Vemu, A]]
[[Category: Wang, S]]
[[Category: Xiang, S]]
[[Category: Yang, C]]
[[Category: Microtubule camsap calmodulin-regulated spectrum-associated proteins ckk cryo-em cryo-electron microscopy]]
[[Category: Structural protein]]