View source for 4yqc


==Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds==
<StructureSection load='4yqc' size='340' side='right'caption='[[4yqc]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4yqc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Haein Haein]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YQC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YQC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EFW:6-{[(1R,3R)-3-HYDROXYCYCLOPENTYL]AMINO}PYRIDINE-3-CARBOXAMIDE'>EFW</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trmD, HI_0202 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=71421 HAEIN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yqc OCA], [http://pdbe.org/4yqc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yqc RCSB], [http://www.ebi.ac.uk/pdbsum/4yqc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yqc ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TRMD_HAEIN TRMD_HAEIN]] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605] 

==See Also==
*[[TRNA methyltransferase|TRNA methyltransferase]]
__TOC__
</StructureSection>
[[Category: Haein]]
[[Category: Large Structures]]
[[Category: Bonnette, W G]]
[[Category: Elkins, P A]]
[[Category: Stuckey, J A]]
[[Category: Knot]]
[[Category: Sam-binding]]
[[Category: Transferase-transferase inhibitor complex]]
[[Category: Trmd]]