View source for 6gjh


==Human Hsp27 (HspB1) alpha-crystallin domain in complex with a peptide mimic of its phosphorylatable N-terminal region==
<StructureSection load='6gjh' size='340' side='right'caption='[[6gjh]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6gjh]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GJH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GJH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gjh OCA], [http://pdbe.org/6gjh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gjh RCSB], [http://www.ebi.ac.uk/pdbsum/6gjh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gjh ProSAT]</span></td></tr>
</table>
== Disease ==
[[http://www.uniprot.org/uniprot/HSPB1_HUMAN HSPB1_HUMAN]] Autosomal dominant Charcot-Marie-Tooth disease type 2F;Distal hereditary motor neuropathy type 2. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry. 
== Function ==
[[http://www.uniprot.org/uniprot/HSPB1_HUMAN HSPB1_HUMAN]] Involved in stress resistance and actin organization. 
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Benesch, J L.P]]
[[Category: Collier, M P]]
[[Category: Chaperone]]
[[Category: Ig-fold]]
[[Category: Shsp]]