View source for 4mhq


==Crystal structure of human primase catalytic subunit==
<StructureSection load='4mhq' size='340' side='right'caption='[[4mhq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4mhq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MHQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MHQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRIM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mhq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mhq OCA], [http://pdbe.org/4mhq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mhq RCSB], [http://www.ebi.ac.uk/pdbsum/4mhq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mhq ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. 
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Large Structures]]
[[Category: An, J Y]]
[[Category: Eom, S H]]
[[Category: Kang, J Y]]
[[Category: Kim, T G]]
[[Category: Lee, J G]]
[[Category: Lee, Y]]
[[Category: Lim, J J]]
[[Category: Park, K R]]
[[Category: Wang, J]]
[[Category: Youn, H S]]
[[Category: Ntp binding]]
[[Category: Nucleus]]
[[Category: Primase]]
[[Category: Replication]]
[[Category: Zinc finger]]