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==Crystal structure of a group II intron in the pre-catalytic state==
<StructureSection load='4ds6' size='340' side='right'caption='[[4ds6]], [[Resolution|resolution]] 3.64&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ds6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oceanobacillus_iheyensis Oceanobacillus iheyensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DS6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ds6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ds6 OCA], [http://pdbe.org/4ds6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ds6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ds6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ds6 ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Group II introns are self-splicing catalytic RNAs that are thought to be ancestral to the spliceosome. Here we report the 3.65-A crystal structure of the group II intron from Oceanobacillus iheyensis in the pre-catalytic state. The structure reveals the conformation of the 5' splice site in the catalytic core and represents the first structure of an intron prior to the first step of splicing.

Crystal structure of a group II intron in the pre-catalytic state.,Chan RT, Robart AR, Rajashankar KR, Pyle AM, Toor N Nat Struct Mol Biol. 2012 Apr 8. doi: 10.1038/nsmb.2270. PMID:22484319<ref>PMID:22484319</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4ds6" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oceanobacillus iheyensis]]
[[Category: Chan, R T]]
[[Category: Pyle, A M]]
[[Category: Rajashankar, K R]]
[[Category: Robart, A R]]
[[Category: Toor, N]]
[[Category: Group ii]]
[[Category: Intron]]
[[Category: Ribonucleic acid]]
[[Category: Rna]]