View source for 5zhm


==Crystal structure of TrmD from Pseudomonas aeruginosa in complex with active-site inhibitor==
<StructureSection load='5zhm' size='340' side='right'  caption='[[5zhm]], [[Resolution|resolution]] 2.76&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5zhm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZHM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZHM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9D3:N-({4-[(diethylamino)methyl]phenyl}methyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide'>9D3</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zhm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zhm OCA], [http://pdbe.org/5zhm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zhm RCSB], [http://www.ebi.ac.uk/pdbsum/5zhm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zhm ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TRMD_PSEAB TRMD_PSEAB]] Specifically methylates guanosine-37 in various tRNAs. 
__TOC__
</StructureSection>
[[Category: Balamkundu, S]]
[[Category: Dedon, P C]]
[[Category: Lescar, J]]
[[Category: Liu, C F]]
[[Category: Nah, Q]]
[[Category: Pasunooti, K K]]
[[Category: Wong, Y W]]
[[Category: Zhong, W]]
[[Category: Transferase]]
[[Category: Trna methyltransferase]]