View source for 2pdi

[[Image:2pdi.jpg|left|200px]]

 {{Structure
|PDB= 2pdi |SIZE=350|CAPTION= <scene name='initialview01'>2pdi</scene>, resolution 1.55&Aring;
|SITE= <scene name='pdbsite=AC1:Nap+Binding+Site+For+Residue+A+500'>AC1</scene> and <scene name='pdbsite=AC2:Zst+Binding+Site+For+Residue+A+600'>AC2</scene>
|LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=ZST:3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE+ACETIC+ACID'>ZST</scene>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span>
|GENE= ALR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00248 Aldo_ket_red]</span>
|RELATEDENTRY=[[2pd5|2PD5]], [[2pd9|2PD9]], [[2pdb|2PDB]], [[2pdc|2PDC]], [[2pdf|2PDF]], [[2pdg|2PDG]], [[2pdh|2PDH]], [[2pdj|2PDJ]], [[2pdk|2PDK]], [[2pdl|2PDL]], [[2pdm|2PDM]], [[2pdn|2PDN]], [[2pdp|2PDP]], [[2pdq|2PDQ]], [[2pdu|2PDU]], [[2pdw|2PDW]], [[2pdx|2PDX]], [[2pdy|2PDY]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pdi OCA], [http://www.ebi.ac.uk/pdbsum/2pdi PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2pdi RCSB]</span>
}}

'''Human aldose reductase mutant L300A complexed with zopolrestat at 1.55 A.'''


==About this Structure==
2PDI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PDI OCA]. 
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Heine, A.]]
[[Category: Klebe, G.]]
[[Category: Steuber, H.]]
[[Category: oxidoreductase]]
[[Category: tim barrel]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr  2 11:57:34 2008''