View source for 3cxy


==Crystal structure of the cytochrome P450 CYP121 P346L mutant from M. tuberculosis==
<StructureSection load='3cxy' size='340' side='right' caption='[[3cxy]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3cxy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CXY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CXY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1n40|1n40]], [[3cxv|3cxv]], [[3cxx|3cxx]], [[3cxz|3cxz]], [[3cy0|3cy0]], [[3cy1|3cy1]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cyp121 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cxy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cxy OCA], [http://pdbe.org/3cxy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cxy RCSB], [http://www.ebi.ac.uk/pdbsum/3cxy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cxy ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/3cxy_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cxy ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Cytochrome P450|Cytochrome P450]]
__TOC__
</StructureSection>
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Leys, D]]
[[Category: Cyp121]]
[[Category: Cytochrome p450]]
[[Category: Cytoplasm]]
[[Category: Heme]]
[[Category: Iron]]
[[Category: Metal-binding]]
[[Category: Monooxygenase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Oxidoreductase]]