View source for 6hvd


==Human SLK bound to a maleimide inhibitor==
<StructureSection load='6hvd' size='340' side='right' caption='[[6hvd]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6hvd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HVD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6HVD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GUQ:3-(1,3-benzothiazol-2-ylamino)-4-(2-methoxyphenyl)pyrrole-2,5-dione'>GUQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6hvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hvd OCA], [http://pdbe.org/6hvd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6hvd RCSB], [http://www.ebi.ac.uk/pdbsum/6hvd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6hvd ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/SLK_HUMAN SLK_HUMAN]] Mediates apoptosis and actin stress fiber dissolution. 
__TOC__
</StructureSection>
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Arrowsmith, C]]
[[Category: Bailey, H J]]
[[Category: Berger, B T]]
[[Category: Bountra, C]]
[[Category: Burgess-Brown, N A]]
[[Category: Delft, F von]]
[[Category: Edwards, A M]]
[[Category: Elkins, J M]]
[[Category: Knapp, S]]
[[Category: Krojer, T]]
[[Category: Pinkas, D]]
[[Category: Salah, E]]
[[Category: Savitsky, P A]]
[[Category: Serafim, R A.M]]
[[Category: Sorrell, F J]]
[[Category: Kinase]]
[[Category: Transferase]]