View source for 2pq2


==Structure of serine proteinase K complex with a highly flexible hydrophobic peptide at 1.8A resolution==
<StructureSection load='2pq2' size='340' side='right' caption='[[2pq2]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2pq2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Engyodontium_album Engyodontium album]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PQ2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dp4|2dp4]], [[2dqk|2dqk]], [[2duj|2duj]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidase_K Peptidase K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.64 3.4.21.64] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pq2 OCA], [http://pdbe.org/2pq2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2pq2 RCSB], [http://www.ebi.ac.uk/pdbsum/2pq2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2pq2 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PRTK_TRIAL PRTK_TRIAL]] Hydrolyzes keratin at aromatic and hydrophobic residues. 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pq/2pq2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pq2 ConSurf].
<div style="clear:both"></div>

==See Also==
*[[Proteinase|Proteinase]]
__TOC__
</StructureSection>
[[Category: Engyodontium album]]
[[Category: Peptidase K]]
[[Category: Dey, S]]
[[Category: Ethayathulla, A S]]
[[Category: Kaur, P]]
[[Category: Sharma, S]]
[[Category: Singh, A K]]
[[Category: Singh, N]]
[[Category: Singh, T P]]
[[Category: Sinha, M]]
[[Category: Somvanshi, R K]]
[[Category: Srinivasan, A]]
[[Category: Complex]]
[[Category: Hydrolase]]
[[Category: Hydrophobic peptide galag]]
[[Category: Proteinase k]]