View source for 2n1h


==Solution structure of the GBII-beta MRH domain W409A point mutant==
<StructureSection load='2n1h' size='340' side='right' caption='[[2n1h]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2n1h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N1H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2N1H FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xqm|4xqm]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gtb1, gls2-beta, SPCC825.02 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2n1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n1h OCA], [http://pdbe.org/2n1h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2n1h RCSB], [http://www.ebi.ac.uk/pdbsum/2n1h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2n1h ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/GLU2B_SCHPO GLU2B_SCHPO]] Subunit of glucosidase 2, which cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins in the endoplasmic reticulum (ER). Specifically required for the cleavage of the final glucose. The subunit beta retains the catalytic subunit alpha in the ER.<ref>PMID:10464333</ref> <ref>PMID:19605557</ref> <ref>PMID:21471007</ref>  

==See Also==
*[[Alpha-glucosidase|Alpha-glucosidase]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Fission yeast]]
[[Category: Damhs, N M]]
[[Category: Olson, L J]]
[[Category: Peterson, F C]]
[[Category: Hydrolase]]
[[Category: Lectin]]
[[Category: Mrh]]