View source for 2ep3


==Solution structure of the C2H2 type zinc finger (region 631-663) of human Zinc finger protein 484==
<StructureSection load='2ep3' size='340' side='right' caption='[[2ep3]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ep3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EP3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF484 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ep3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ep3 OCA], [http://pdbe.org/2ep3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ep3 RCSB], [http://www.ebi.ac.uk/pdbsum/2ep3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ep3 ProSAT], [http://www.topsan.org/Proteins/RSGI/2ep3 TOPSAN]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/ZN484_HUMAN ZN484_HUMAN]] May be involved in transcriptional regulation. 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ep/2ep3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ep3 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Abe, H]]
[[Category: Kigawa, T]]
[[Category: Kobayashi, N]]
[[Category: Koshiba, S]]
[[Category: Li, H]]
[[Category: Structural genomic]]
[[Category: Saito, K]]
[[Category: Sato, M]]
[[Category: Tochio, N]]
[[Category: Tomizawa, T]]
[[Category: Yokoyama, S]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Transcription]]
[[Category: Zf-c2h2]]