View source for 2eki


==Solution structures of the TGS domain of human developmentally-regulated GTP-binding protein 1==
<StructureSection load='2eki' size='340' side='right' caption='[[2eki]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2eki]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EKI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EKI FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DRG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2eki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eki OCA], [http://pdbe.org/2eki PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2eki RCSB], [http://www.ebi.ac.uk/pdbsum/2eki PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2eki ProSAT], [http://www.topsan.org/Proteins/RSGI/2eki TOPSAN]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/DRG1_HUMAN DRG1_HUMAN]] Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest. 
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ek/2eki_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eki ConSurf].
<div style="clear:both"></div>

==See Also==
*[[GTP-binding protein|GTP-binding protein]]
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Harada, T]]
[[Category: Kigawa, T]]
[[Category: Koshiba, S]]
[[Category: Structural genomic]]
[[Category: Sato, M]]
[[Category: Watanabe, S]]
[[Category: Yokoyama, S]]
[[Category: Drg]]
[[Category: Drg 1]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nedd-3]]
[[Category: Nedd3]]
[[Category: Neural precursor cell expressed developmentally down-regulated protein 3]]
[[Category: Nppsfa]]
[[Category: Protein nedd3]]
[[Category: Rsgi]]
[[Category: Signaling protein]]