View source for 2xd9


==STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-4,6,7-Trihydroxy-2-((E)-prop-1- enyl)-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid==
<StructureSection load='2xd9' size='340' side='right' caption='[[2xd9]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2xd9]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43504 Atcc 43504]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XD9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=XD9:(4R,6R,7S)-4,6,7-TRIHYDROXY-2-[(1E)-PROP-1-EN-1-YL]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC+ACID'>XD9</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2c57|2c57]], [[2wks|2wks]], [[2c4v|2c4v]], [[2xda|2xda]], [[2xb9|2xb9]], [[1j2y|1j2y]], [[2c4w|2c4w]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xd9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd9 OCA], [http://pdbe.org/2xd9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xd9 RCSB], [http://www.ebi.ac.uk/pdbsum/2xd9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd9 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/AROQ_HELPY AROQ_HELPY]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169] 
__TOC__
</StructureSection>
[[Category: 3-dehydroquinate dehydratase]]
[[Category: Atcc 43504]]
[[Category: Castedo, L]]
[[Category: Fox, G C]]
[[Category: Gonzalez-Bello, C]]
[[Category: Hawkins, A R]]
[[Category: Lamb, H]]
[[Category: Lapthorn, A J]]
[[Category: Llamas-Saiz, A L]]
[[Category: Otero, J M]]
[[Category: Paz, S]]
[[Category: Raaij, M J.van]]
[[Category: Tizon, L]]
[[Category: Aromatic amino acid biosynthesis]]
[[Category: Lyase]]