View source for 5knp


==Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Hypoxanthin-9-yl)pyrrolidin-3-yl)-oxymethanephosphonic acid==
<StructureSection load='5knp' size='340' side='right' caption='[[5knp]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5knp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KNP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6W7:[(3~{S},4~{R})-4-(6-oxidanylidene-1~{H}-purin-9-yl)pyrrolidin-3-yl]oxymethylphosphonic+acid'>6W7</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5knq|5knq]], [[5kny|5kny]], [[5knr|5knr]], [[5kns|5kns]], [[5knv|5knv]], [[5knu|5knu]], [[5knt|5knt]], [[5knx|5knx]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hpt, hprT, Rv3624c, MTCY15C10.28 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hypoxanthine_phosphoribosyltransferase Hypoxanthine phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.8 2.4.2.8] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5knp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5knp OCA], [http://pdbe.org/5knp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5knp RCSB], [http://www.ebi.ac.uk/pdbsum/5knp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5knp ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Hypoxanthine phosphoribosyltransferase]]
[[Category: Myctu]]
[[Category: Eng, W S]]
[[Category: Guddat, L W]]
[[Category: Keough, D T]]
[[Category: Rejman, D]]
[[Category: Complex]]
[[Category: Inhibitor]]
[[Category: Nucleoside phosphonate]]
[[Category: Phosphoribosyltransferase]]
[[Category: Transferase-inhibitor complex]]