View source for 4ho8


==Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-glucose and thymidine==
<StructureSection load='4ho8' size='340' side='right' caption='[[4ho8]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4ho8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aneth Aneth]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HO8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HO8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ho0|4ho0]], [[4ho2|4ho2]], [[4ho3|4ho3]], [[4ho4|4ho4]], [[4ho5|4ho5]], [[4ho6|4ho6]], [[4ho9|4ho9]], [[4hoc|4hoc]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rmlA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=143495 ANETH])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-1-phosphate_thymidylyltransferase Glucose-1-phosphate thymidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.24 2.7.7.24] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ho8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ho8 OCA], [http://pdbe.org/4ho8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ho8 RCSB], [http://www.ebi.ac.uk/pdbsum/4ho8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ho8 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/Q9AGY4_ANETH Q9AGY4_ANETH]] Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity).[RuleBase:RU003706] 
__TOC__
</StructureSection>
[[Category: Aneth]]
[[Category: Glucose-1-phosphate thymidylyltransferase]]
[[Category: Chen, T J]]
[[Category: Chien, W T]]
[[Category: Lin, C C]]
[[Category: Wang, W C]]
[[Category: Nucleotide binding]]
[[Category: Thymidylyltransferase]]
[[Category: Transferase]]