View source for 3sa3


==Crystal structure of wild-type HIV-1 protease in complex with AG23==
<StructureSection load='3sa3' size='340' side='right' caption='[[3sa3]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sa3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SA3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3SA3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=23X:N~2~-ACETYL-N-[(2S,3R)-4-{(1,3-BENZOTHIAZOL-6-YLSULFONYL)[(2S)-2-METHYLBUTYL]AMINO}-3-HYDROXY-1-PHENYLBUTAN-2-YL]-L-ISOLEUCINAMIDE'>23X</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3sa4|3sa4]], [[3sa5|3sa5]], [[3sa6|3sa6]], [[3sa7|3sa7]], [[3sa8|3sa8]], [[3sa9|3sa9]], [[3saa|3saa]], [[3sab|3sab]], [[3sac|3sac]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol, pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3sa3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sa3 OCA], [http://pdbe.org/3sa3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3sa3 RCSB], [http://www.ebi.ac.uk/pdbsum/3sa3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3sa3 ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Nalam, M N.L]]
[[Category: Schiffer, C A]]
[[Category: Aid]]
[[Category: Aspartyl protease]]
[[Category: Drug design]]
[[Category: Drug resistance]]
[[Category: Hiv-1 protease]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protease inhibitor]]