View source for 5hdk


==Crystal structure of heat shock factor 2-DBD==
<StructureSection load='5hdk' size='340' side='right' caption='[[5hdk]], [[Resolution|resolution]] 1.32&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5hdk]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HDK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HDK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hdg|5hdg]], [[5hdn|5hdn]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSF2, HSTF2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hdk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hdk OCA], [http://pdbe.org/5hdk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hdk RCSB], [http://www.ebi.ac.uk/pdbsum/5hdk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hdk ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/HSF2_HUMAN HSF2_HUMAN]] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked. 
__TOC__
</StructureSection>
[[Category: Human]]
[[Category: Feng, H]]
[[Category: Liu, W]]
[[Category: Wang, D C]]
[[Category: Hsf1-dbd]]
[[Category: Transcription]]