View source for 3cup


==Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235==
<StructureSection load='3cup' size='340' side='right' caption='[[3cup]], [[Resolution|resolution]] 3.09&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3cup]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3CUP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cup OCA], [http://pdbe.org/3cup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3cup RCSB], [http://www.ebi.ac.uk/pdbsum/3cup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3cup ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cu/3cup_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cup ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Corper, A L]]
[[Category: Teyton, L]]
[[Category: Wilson, I A]]
[[Category: Yoshida, K]]
[[Category: Glycoprotein]]
[[Category: Histocompatability antigen]]
[[Category: I-ag7]]
[[Category: Immune response]]
[[Category: Immune system]]
[[Category: Membrane]]
[[Category: Mhc class ii]]
[[Category: Mhc ii]]
[[Category: Transmembrane]]