View source for 3is5


==Crystal structure of CDPK kinase domain from toxoplasma Gondii, TGME49_018720==
<StructureSection load='3is5' size='340' side='right' caption='[[3is5]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3is5]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgm Toxgm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IS5 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGME49_018720 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=508771 TOXGM])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3is5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3is5 OCA], [http://pdbe.org/3is5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3is5 RCSB], [http://www.ebi.ac.uk/pdbsum/3is5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3is5 ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/is/3is5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3is5 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Calcium/calmodulin-dependent protein kinase]]
[[Category: Toxgm]]
[[Category: Arrowsmith, C H]]
[[Category: Artz, J D]]
[[Category: Bochkarev, A]]
[[Category: Bountra, C]]
[[Category: Cossar, D]]
[[Category: Edwards, A M]]
[[Category: Hui, R]]
[[Category: Hutchinson, A]]
[[Category: Kozieradzki, I]]
[[Category: Lin, Y H]]
[[Category: MacKenzie, F]]
[[Category: Structural genomic]]
[[Category: Senisterra, G]]
[[Category: Weigelt, J]]
[[Category: Wernimont, A K]]
[[Category: Atp-binding]]
[[Category: Cdpk]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Parasitology]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Sgc]]
[[Category: Toxoplasma gondii]]
[[Category: Transferase]]